GLUTATHIONE REDUCTASE, REDUCED GLUTATHIONE AND CERULOPLASMIN IN DIETHYLDITHIOCARBAMATE TREATED RATS
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Liver glutathione and glutathione reductase response of endotoxin-treated mice.
The decrease in the level of liver glutathione (GSH) in endotoxin-treated mice was in part due to formation of glutathione disulfide (GSSG). An electron-generating system (EGS) had no effect when incubated with soluble liver extracts from normal controls but resulted in recovery of GSH amounting to 25% in endotoxin-treated animals. Incubation in the absence of the EGS caused a decline of 16% in...
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Introduction Reduced glutathione, most commonly called glutathione or GSH, is a relatively small molecule ubiquitous in living systems. Occurring naturally in all human cells, GSH is a water-phase orthomolecule. Its intracellular depletion ultimately results in cell death and its clinical relevance has been researched for decades. GSH is the smallest intracellular thiol (–SH) molecule. Its high...
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ژورنال
عنوان ژورنال: Journal of Evolution of medical and Dental Sciences
سال: 2013
ISSN: 2278-4748,2278-4802
DOI: 10.14260/jemds/291